Diagnosis of Malaria by OptiMal Immuno-Chromatographic Antigen and Microscopy: A Comparison
نویسنده
چکیده
The objective of the study was to compare OptiMAL test method with conventional microscopy for the detection of Malaria. 150 patients below the age of 15 years who were clinically suspected to be suffering from Malaria from July’14 Feb’15 were studied. OptiMAL test and Light microscopic examination of thick and thin blood films were done and the results compared. Out of 150 suspected cases of malaria 80 patients (46 falc, 34 viv) were positive with microscopy while only 76 patients (43 falc, 33 viv) were positive with OptiMAL. The sensitivity and specificity for Plasmodium falciparum was 93.47%, and 98.57%, and for Plasmodium vivax 97.05% and 100%. OptiMal test is simple, effective and rapid diagnostic test which can be used with or without traditional blood film examination for detection of both P. vivax and P. falciparum.
منابع مشابه
Comparison of real time polymerase chain reaction with microscopy and antigen detection assay for the diagnosis of malaria.
OBJECTIVE To determine the sensitivity of a real time polymerase chain reaction (PCR) for malaria diagnosis and to compare its accuracy with microscopy and an antigen based rapid diagnostic test (OptiMal). STUDY DESIGN Cross-sectional analytical study. PLACE AND DURATION OF STUDY Military Hospital, Armed Forces Institute of Transfusion and Armed Forces Institute of Pathology, Rawalpindi, fr...
متن کاملCost-Effectiveness analysis of malaria diagnosis techniques in patients with suspected malaria in Hormozgan province- 2012
Introduction: Since ancient times Malaria in Iran has been considered as a serious health risk, especially in Hormozgan Province, as no other disease like Malaria has imposed irreparable financial and life losses to the country. Since saving costs in the healthcare sector comes as first priority in most countries, this study aims at launching a cost-effectiveness analysis on malaria diagnosis d...
متن کاملComparison of two commercial assays with expert microscopy for confirmation of symptomatically diagnosed malaria.
Conventional light microscopy has been the established method for malaria diagnosis. However, recently several nonmicroscopic rapid diagnostic tests have been developed for situations in which reliable microscopy may not be available. This study was conducted to evaluate the diagnostic performance of a recently introduced ICT Malaria Pf/Pv test. This assay detects Plasmodium falciparum histidin...
متن کاملComparison of optimal malarial test with light microscopy for the diagnosis of malaria.
OBJECTIVE To evaluate the efficacy of a parasite lactate dehydrogenase-based immunochromatographic antigen detection assay (optimal) against conventional light microscopy in the diagnosis of malaria at Military Hospital, Rawalpindi and Department of Pathology Army Medical College Rawalpindi from August to October 2002 in patients reporting sick with history suggestive of malaria. METHODS The ...
متن کاملComparison of the OptiMAL test with PCR for diagnosis of malaria in immigrants.
The OptiMAL test (Flow Inc., Portland, Oreg.), which detects a malaria parasite lactate dehydrogenase (pLDH) antigen, has not been evaluated for its sensitivity in the diagnosis of malaria infection in various epidemiological settings. Using microscopy and a PCR as reference standards, we performed a comparison of these assays with the OptiMAL test for the detection of Plasmodium falciparum and...
متن کامل